Your Skin's Enemy

Don't Deviate. Hitting the hay at a consistent time is one of the most important changes you can make, sleep experts say. Consistency normalizes your circadian rhythms, your body's internal clock, so you're the most deeply asleep in the first half of the night. This makes waking up in the morning easier. Most people benefit from a bedtime between 10 p.m. and midnight and a wake-up time between 6 and 8 a.m., Campbell says. Whatever you choose, stick to it faithfully, even on weekends and holidays.

Simmer Down. Once you've chosen a bedtime, prepare your body to fall asleep at that time. About an hour before you go to bed, dim your lamps and extinguish strong overhead lights. Lower light gives your brain the signal that it's almost time to sleep, Campbell says. At least an hour before bed, switch to quiet activities, says Edward O'Malley, Ph.D., director of Norwalk Hospital's Sleep Disorders Center in Norwalk, Conn. Read a book or magazine that's not challenging. If you watch television, opt for sitcom reruns; they're lighthearted, short, and not surprising.
BR> For instance, in India, there is also an epidemic of low body-weight (LBW) diabetes (15)--a phenomenon that clearly points to the existence of environmental factors unrelated to obesity that are involved in the pathogenicity of diabetes, and supports the dysox model of diabetes. A growing number of free radicals, transcription factors, enzymes, and proteins has been--and continues to be--implicated in the pathogenesis of diabetes, including: (1) nitric oxide; (16,17) (2) inducible nitric oxide synthase (iNOS); (18) (3) mitochondrial uncoupling proteins

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